Proper use of anti-seize compound can make future bolt removal a snap. If you have ever broken off a bolt during removal, I bet you wish someone had used it when it was originally installed!! The best place to use this compound is where steel comes in contact with aluminum. In the picture above, I am using it on the bolts for the aluminum thermostat housing. This is a great example as these small bolts are often broken off when changing a thermostat. Anti-seize can help prevent dissimilar metal corrosion, particularly in areas where they use salt on the roads. I wipe a thin film of this compound on my wheel hubs when installing aluminum alloy wheels. Keeps them from seizing together over time.
There are places where you should NOT use anti-seize compound. NEVER use it on lug bolts or other critical high stress bolts such as those found on brake calipers or suspension components. These are usually steel on steel contact anyway and anti-seize will only help the bolt loosen up...and that you do NOT want!